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Better Mood and Mental Health with B-Vitamins: B1, B6 and B12

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Better Mood and Mental Health with B-Vitamins: B1, B6 and B12

A person’s mood and emotional state are influenced by health conditions and body compounds such as hormones, brain chemicals, and nutrients. The nerve-nourishing nutrients Vitamins B1, B6 and B12 have been found to play key roles in keeping a healthy mood as explained by the following:

Vitamin B1 (Thiamine) keeps the brain active and energized  

The brain, being considered as a metabolically active organ accounting for over 20% of the body’s total energy expenditure, is selective when it comes to its source of energy. It almost exclusively relies on glucose obtained from the carbohydrates that we eat or are processed by the body. The process of converting glucose into brain energy essentially requires Vitamin B1 or Thiamine.  This makes Vitamin B1 a crucial nutrient to keep the brain energized.

Vitamin B6 (Pyridoxine) helps the brain form the neurotransmitters, the brain chemicals responsible for one’s mood and mental function

Neurotransmitters are brain chemicals that influence mood and mental function. Vitamin B6 or Pyridoxine contributes to a healthy brain function by being an essential nutrient for the production of a number of neurotransmitters such as dopamine, serotonin, gamma-aminobutyric acid (GABA), noradrenaline and melatonin. Dopamine plays a role in reactions involved on how pleasure is felt while serotonin contributes to feelings of well-being. GABA is needed to regulate or calm brain activity and help reduce anxiety. Noradrenaline helps in coping with stress and in becoming active while melatonin is important in maintaining a healthy sleep-wake cycle. 

Vitamins B6 and B12 (Cyanocobalamin) help clear away metabolic by-products linked with depression

Whenever the body processes or metabolizes protein, it produces a substance known as homocysteine. Homocysteine accumulation has been linked to the development of depression.  It was reported that up to 30% of depressed patients were found to have elevated homocysteine levels. Thankfully, the body is able to naturally clear away homocysteine through reactions involving Vitamin B6 (Pyridoxine) and Vitamins B12 (Cobalamin). Maintaining healthy levels of Vitamins B6 and B12 may therefore be seen as a way to prevent homocysteine buildup. 

Supplementation with B vitamins has been suggested to support a healthy mood and mental well-being

Seeing that B vitamins play numerous roles in keeping a healthy mood, it is no surprise that deficiencies of these B vitamins may lead to mood disorders. Studies have shown that deficiencies in B vitamins are associated with the development of various mood disorders and supplementation of B vitamins support a healthy mood.

 In a study done on 35,000 older adults, it was shown that higher intakes of Vitamin B6 and B12 were associated with a lower risk of developing depressive symptoms by about 7 years. In another clinical trial, treatment with vitamin B complex for 3 months led to lower levels of perceived personal strain and sad mood compared to those who were not given vitamin B complex. 

These studies suggest that intake of nerve-nourishing B vitamins is supportive of mental well-being given their various roles in multiple brain processes involved in regulating mood. Click here to learn more about B-vitamins.

For individuals feeling symptoms of depression, it is always best to seek professional help or to consult a doctor.

References: 

Young LM et al. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress Effects on Healthy and ‘At-Risk’ Individuals. Nutrients. 2019;11(9):2232. Published 2019 Sep 16. doi:10.3390/nu11092232

Stough C et al. The effect of 90 day administration of a high dose vitamin B-complex on work stress Hum Psychopharmacol. 2011;26(7):470-476. doi:10.1002/hup.1229

Kennedy DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy -A Review. Nutrients. 2016;8(2):68. Published 2016 Jan 27.doi:10.3390/nu8020068

Seppälä J et al. Association between vitamin b12 levels and melancholic depressive symptoms a Finnish population-based study. BMC Psychiatry. 2013;13:145. Published 2013 May 24. doi:10.1186/1471-244X-13-145

Sangle P et al. Vitamin B12 Supplementation: Preventing Onset and Improving Prognosis of Depression Cureus. 2020;12(10):e11169. Published 2020 Oct 26. doi:10.7759/cureus.11169

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Sodium Ascorbate: The Benefits of a Non-Acidic Vitamin C

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What is Vitamin C?

Vitamin C is a widely used water-soluble vitamin known to play a vital role as in a variety of body functions. It is one of the essential nutrients needed for building and strengthening body tissues owing to its action in the formation of a firm collagen, the cement-like substance that binds the body cells together to form strong tissues.  It is therefore important in the formation of healthy skin, blood vessel walls, cartilage, strong bones and teeth, as well as in promoting faster healing of wounds.

Being touted as the body’s “prime” immune system boosting nutrient, vitamin C is popularly known for its protective function against stress and certain diseases such as anemia, immune system deficiencies, asthma, viral infections and cardiovascular illnesses.

Vitamin C is also reported to promote cardiovascular health and helps lower blood cholesterol.

As a potent antioxidant, Vitamin C strengthens the immune system and increases body resistance to stress and infections.  Specifically, Vitamin C protects the body’s soldiers, the white blood cells, from the damaging effects of free radicals with its antioxidative properties. Vitamin C stimulates the white blood cells in clearing away infectious microbes. 

Though Vitamin C does not offer a cure for diseases such as the common cold, several studies suggest that vitamin C helps in alleviating the disturbing symptoms of cold and in shortening its duration.  This can reduce the risk for dreaded lung infections such as pneumonia.

Ascorbic acid and Sodium ascorbate, are they the same?

Many are quite reluctant in taking ascorbic acid or the so- called ordinary or “acidic” Vitamin C because of its potential effect in irritating the lining of the stomach of susceptible individuals. Thus, vitamin C is buffered or neutralized with the mineral sodium as the salt of vitamin C to become sodium ascorbate. Labelled as the non-acidic vitamin C, sodium ascorbate is in alkaline or buffered form, therefore it will cause less stomach irritation as compared with ascorbic acid.

Sodium ascorbate delivers the same benefits of vitamin C to the human body without causing the possible gastric irritating effects of ascorbic acid.

Since sodium ascorbate is less likely associated with hyperacidity, it is commonly recommended to individuals who experience gastrointestinal complaints such as heartburn, flatulence, nausea and diarrhea.

How safe is Vitamin C?

Despite its sodium content, Sodium ascorbate in recommended doses is safe for hypertensive individuals. Adults, especially those with cardiovascular disease, on a low-salt diet are advised to limit their total daily sodium intake to less than 1,500 mg/day.

Sodium ascorbate contains only 10% – 11% sodium.  Approximately, 1000 mg of sodium ascorbate, equivalent to two 500mg capsules, provides 889 mg of vitamin C and only 111 mg of sodium.  1-2 capsule(s) of 500 mg of sodium ascorbate taken daily will only give approximately 111 mg sodium.

Vitamin C is usually well tolerated and generally no adverse reactions are expected when it is taken at recommended doses. Vitamin C may cause diarrhea if taken in large amounts.

Vitamin C should be given with caution in patients with hyperoxaluria because large amounts may lead to the formation of calcium oxalate stones in the kidney. Urinary stone formers appear to be at higher risk for calculi if individuals take large doses of vitamin C daily. 

Large doses of vitamin C may also result in a false positive glucose test in the urine and may interfere with the diagnosis of diabetes mellitus.


References:

Vitamin C. Oregon State University Linus Pauling Institute Micronutrient Information Center.

Gombart AF, Pierre A, Maggini S. A Review of Micronutrients and the Immune System-Working in Harmony to Reduce the Risk of Infection. Immune Defense, Vitamin C, Vitamins

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REGERON VITA with CPE

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Support your child’s holistic growth and development, physically and mentally, with REGERON VITA WITH CPE.

Packed with 14 nutrients including Chlorella Pure Extract (CPE), Regeron Vita with CPE helps boost children’s growth, energy, immune system and mental function. 

Regeron Vita with CPE Syrup and Drops are available in delicious bubblegum flavor that kids and babies would surely enjoy.

A daily dose of Regeron Vita with CPE helps your kids get all of these health benefits:

•           Growth Factors, such as Chlorella Pure Extract and Amino Acid Lysine, plus Vitamin D which promotes calcium absorption and bone growth

•           Immune System Enhancers, Vitamin A, C, E, CPE, and Zinc

•           Energy Boosting B Vitamins, Vitamins B1, B3, B6, B9, and B12

•           Blood Building Nutrients, Vitamin B9 and Vitamin B12

•           Brain Enhancing B Vitamins and Taurine

Regeron Vita with CPE is available in both Syrup (for children ages 1 to 9 years old), and Drops (for infants ages 6 months to 1 year old)

Regeron Vita with CPE Syrup and Drops are widely available in leading drugstores, nationwide.

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Taking Care of your Babies Delicate Nose with Flo Baby Nasal Spray

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Babies breathe exclusively through their nose on the first few months after birth. This allows them to feed, swallow, and breathe at the same time. Since babies have tiny nasal passages, even the smallest amount of mucus may interfere with breathing thus disrupting their feeding and sleeping. Therefore, it is important that their nasal airways are kept clean and clear of mucus, allergens and other irritants.

Flo™ Baby Nasal Spray is specifically designed for babies’ sensitive and delicate nose to gently clean and wash away the excess mucus making your baby breathe easier.

Flo™ Baby Nasal Spray has a specialized COMOD® (Continuous MonoDose) system, which makes sure that the solution in the bottle is sterile and free of contaminants.

Flo™ Baby Nasal Spray is isotonic which means that the solution has the same concentration as the body’s own fluid. It is also non-medicated and preservative-free therefore, Flo™ Baby Nasal Spray is non-irritating and gentle to the babies’ delicate nose.

Flo™ Baby Nasal Spray may be sprayed quickly at any angle, even upside down. This means that the baby can assume any position of comfort, even lying down, while using the spray.

Flo™ Baby Nasal Spray delivers the solution in a gentle micro- mist spray allowing the solution to be dispersed evenly.

Flo™ Baby Nasal Spray provides metered-doses to ensure that the baby receives the right amount of spray for each use.

Flo Baby™ Nasal Spray is handy and easy to carry anywhere especially during travel.

For more information and directions for use, please read the Consumer Information Leaflet in the packaging.

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Polynerv E with Lecithin Tablet

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Nothing but the best for your health—22 Nutrients in every tablet of a Premium Dietary Supplement.

Polynerv E with Lecithin is specially formulated to meet the daily needs of the demanding lifestyle. It offers a wide array of high-quality vitamins, minerals and special ingredients such as the potent cardioprotectors, Coenzyme Q10, Vitamin E and Omega 3 Fatty Acids, among others.

Get all these benefits and more from each tablet of Polynerv E with Lecithin:

•           Immune System boosters, such as Vitamins A & E, Zinc, Selenium, Omega 3, to strengthen your body’s natural defense in preventing and fighting off infection.

•           Antioxidants, such as CoQ10 and Vitamin E, to help battle the harmful effects of free radicals.

•           Energy Boosters, B Vitamins and Ginseng, to boost both your mental and physical stamina.

•           Cardioprotecting nutrients, like CoQ10, Ginseng, and Omega-3 Fatty Acids, to support a healthy heart and blood circulation.

•           Brain-Boosting and Nerve-Nourishing nutrients, such as B vitamins, Lecithin and Korean Ginseng.

•           Healthy Eyesight and Glowing Skin, from Vitamins A and E, and lutein, beta-carotene and lycopene.

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A woman working on a computer laptop, smiling. Aminobrain product box, seen on the left side of the image.

Aminobrain Tablet

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Feed your mind and body with tissue building and brain boosting nutrients. Aminobrain tablet offers a special blend of 32 ingredients which includes Essential Amino Acids, B Vitamins, Taurine and Lecithin, all in one tablet.

Aminobrain Tablet is packed with a wide array of ingredients offering multiple health benefits.

Essential Amino Acids, the “building blocks of the proteins,” are needed for tissue growth, repair and formation of healthy muscle, bones, hormones, antibodies, blood elements, and neurotransmitters. Amino acids are especially helpful: 

•           at times of rapid tissue growth (e.g., pregnancy, body building)

•           when tissue building is necessary (e.g., recovery from illness or surgery)

•           if diet fails to meet nutrient requirement (e.g., loss of appetite, special restricted diets)

A comprehensive array of vitamins, Vitamins A, C, D, E plus 8 B Vitamins:

•           Vitamin A for healthy eyesight, healthy skin and blood vessels, and improved immunity.

•           B Vitamins (B1, B2, B3, B5, B6, B7, B9, B12) for nerve and brain health, blood formation and energy boosting.

•           Vitamin D for enhanced calcium absorption and bone health.

•           Vitamins C and E as powerful antioxidants to boost the immune system, fight free radicals and protect heart health.

A variety of minerals, including Zinc, to help boost the immune system, plus Selenium, Magnesium, Manganese, Chromium, Copper and Molybdenum to support the body’s various metabolic processes.

Special Nutrients Lecithin and Taurine to support healthy brain development and activity.

Aminobrain tablet also comes in an Enteric Coated Tablet, making it gentle to the stomach, and packed in Aluminum-to-Aluminum blister packaging, to protect its potency from heat, light and moisture.

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Nutricap Tablet

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Give your body what it deserves. Get 26 vitamins, minerals plus special nutrients in just 1 tablet NUTRICAP.

Packed with numerous health benefits, Nutricap tablet is your cost-effective choice for a broad and high-quality dietary supplement. 

Know the health benefits of the following nutrients:

• Boost the immune system with the antioxidants, Vitamins A, C, E, Zinc and more to help fight against infection and harmful effects of free radicals. 

• Support the heart and circulatory with Lycopene, Lecithin, Ginseng, Vitamins C, and E

• Promote nerve nourishment with Vitamin B complex

• Enhance brain and memory with Gingko Biloba, Ginseng, Vitamin B Complex 

• Provide Eye protection with colorful nutrients, Lutein, Rutin, Zeaxanthin, and Lycopene plus Vitamin A 

• Rejuvenate the body and skin with Vitamins A, C, and E

• Revitalize and energize the body with Ginseng, Iron and Vitamin B complex.

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Woman wearing earrings, doing nasal washing, holding a blue bottle pointed at nostrils.

Flo Sinus Care

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Need to flush away excess or dried up mucus and other debris from your sinus and nasal passages? Flo Sinus Care washes both the nasal and sinus cavities, thoroughly yet gently.

Flo Sinus Care uses a large volume irrigating solution delivered at low positive pressure to reach and clean not only the nasal cavities, but also the sinuses.

Flo Sinus Care is also specifically formulated to match the natural fluids found in the nose. Flo Sinus Care’s irrigating solution is isotonic, having the same salt concentration as that of the natural nasal fluids to make Flo Sinus Care gentle to use, without the sting. 

Flo Sinus Care thoroughly cleanses and is safe to use. Flo Sinus Care is non-medicated. This means you can safely use Flo Sinus Care together with other nasal medications. Flo Sinus Care may be used even by pregnant women, breastfeeding mothers, the elderly, and children 5 and above as supervised by an adult.

If symptoms persist, consult your doctor.

HOW TO USE?
A woman holding and massaging her left palm surrounded with nerve elements, B vitamins, and blue circles around her hand.

How B Vitamins Help Keep Our Nerves Healthy and Safe from Nerve Damage

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Among the B vitamins, there is a group called nerve vitamins due to the important role these vitamins play in nourishing and maintaining the health of our nerves and these are: B1, B6, and B12.  

Vitamin B1, or Thiamine, allows our body to convert the sugar and other carbohydrates we eat into energy that is essential for the brain and nerves to function. The importance of this role is further highlighted considering that our brain and nerves almost exclusively rely on carbohydrates as their chief fuel source for energy.

Vitamin B6, or Pyridoxine, plays a vital role in the formation of neurotransmitters, the chemicals that allow nerves to properly transfer impulses and communicate with each other and even be responsible for maintaining a healthy mood. Some examples of neurotransmitters include dopamine and serotonin, the so-called “happy hormones”.

Vitamin B12, or Cobalamin, supports the formation and maintenance of healthy nerve tissues, specifically the myelin sheath. The nerves are like cables or wires that carry the electrical impulses between your brain and the different parts of the body. Just like how cables are coated with rubber insulators to efficiently conduct the transmission of electricity, the nerves have myelin sheath. The myelin sheath is an insulating layer around nerves that also allows electrical impulses to transmit quickly and efficiently along the nerve fibers. 

Deficiencies involving B vitamins due to improper nutrition or diseases result in nerve damage or neuropathy, which may be felt as numbness, ‘pins-and-needles’ sensation, tingling, or weakness particularly affecting the hands and feet.  Certain conditions like diabetes, traumatic nerve impingement or aging may also cause neuropathies and would need supplementation of nerve vitamins to allow nerve healing and recovery. 

Use of B-complex vitamins formulated with high doses of vitamins B1, B6, and B12 have been shown by numerous clinical studies to help relieve symptoms of neuropathies and promote nerve recovery.

For proper advice and to know more on how to take care of your nerves before it is too late, it is always best to consult your doctor.

Doctor, Hand, Holding, A, Liver, Shape, Made, From, Pink, Paper. With a stethoscope on the neck.

FAQs on Silybin-Phosphatidylcholine Complex and its Benefits on Liver Health and Vitality

Written on . Posted in Health Articles.

Our liver is an essential organ of our body which performs hundreds of functions including removal of toxins from the blood circulation, metabolism of food nutrients, and processing  of medications. Our liver may be subjected to various forms of injuries caused by infections, toxins, and unhealthy lifestyle leading to liver diseases. A compound that has been well recognized to protect our liver from further injury is the silybin-phosphatidylcholine complex.

Get to know more about this widely used compound and how it can help support your liver health.

1. What is silybin-phosphatidylcholine?

Silybin-phosphatidylcholine is a complex of two widely known liver protectors, silybin and phosphatidylcholine. Silybin is the major component of Silymarin, an extract of the milk thistle (Silybum marianum) plant which has been used for thousands of years as remedy for various ailments including those of the liver.

Silybin is the most bioactive component of Silymarin. It is known to provide multiple health benefits particularly for the liver through its antioxidative, anti-inflammatory, regenerative, and protective biologic activities.

Phosphatidylcholine, a type of phospholipid that naturally makes up the body cells is essential for maintaining the cell covering or membranes. Phosphatidylcholine is also reported to improve cardiovascular and liver health. It lowers blood cholesterol and increases the levels of HDL (high density lipoproteins) or the so called “good cholesterol”.

2. What benefits do silybin and phosphatidylcholine provide to the liver?

Silybin is considered as the major constituent of silymarin, a plant extract recognized for its benefits to the liver.  It was officially classified by the World Health Organization (WHO) in the 1970s as a drug with liver-protecting properties.

Studies on silybin have shown that it possesses antioxidative, anti-inflammatory, regenerative, and liver-protecting actions which may directly address the damaging processes involved in liver illnesses such as fatty liver.

Silybin is reported to have both protective and regenerative effects. Silybin as a powerful antioxidant reduces the harmful free radicals formed by toxins that damage the liver cell membrane.  Silybin also supports the production of glutathione,  the liver’s natural antioxidant.  Silybin activates the liver’s metabolism to produce more proteins thus stimulating the liver’s regenerative ability and the formation of new liver cells.

Owing to these multiple actions in protecting the liver cells, silybin has been widely used as a support in the management of various liver conditions such as different forms of hepatitis, drug induced liver injury and fatty liver disease.

On the other hand, phosphatidylcholine may also serve as a building block for cell membranes that help repair injured liver cells aside from improving the absorption of silybin.

3. Why is silybin combined with phosphatidylcholine?

One major limitation of silybin is that it is poorly absorbed by the digestive tract when taken orally as silymarin alone. This is due to its large molecular size and its poor ability to mix with lipids that make up the membranes of the cells lining the absorptive layer of the small intestine.

However, by combining silybin with phosphatidycholine which is a principal component of cell membranes, a lipid-compatible complex is formed which significantly improves its absorption. This enhances the availability of silybin in the blood circulation by as much as 4.6 times.

The formation of the silybin-phosphatidylcholine complex allows the enhanced delivery of silybin’s protective benefits to the liver.

4. What are the clinical benefits of combining silybin with phosphatidylcholine?

The silybin-phosphatidylcholine complex provides a dual support for the liver through a combination of well-known liver-protecting agents.

The clinical benefit of  silybin-phosphatidylcholine has been documented in a study on patients with non-alcoholic fatty liver disease. The patients who were treated with a formulation of silybin-phosphatidylcholine with vitamin E twice daily for 12 months showed significant improvements in the markers of liver injury such as serum liver enzymes, SGPT and SGOT, and liver biopsy, compared with placebo.

Ask your doctor about naturally derived liver-protecting agents like silybin-phosphatidylcholine and their benefits to your liver health.

References:

  1. Barzaghi N, Crema F, Gatti G, Pifferi G, Perucca E. Pharmacokinetic studies on IdB 1016, a silybin- phosphatidylcholine complex, in healthy human subjects. Eur J Drug Metab Pharmacokinet. 1990;15(4):333-338. doi:10.1007/BF03190223
  2. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med. 2012;52(9):1658-1665. doi:10.1016/j.freeradbiomed.2012.02.008
  3. Silybin-phosphatidylcholine complex. Monograph. Altern Med Rev. 2009;14(4):385-390.

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